Oligonucleotide-directed proximity-interactome mapping (O-MAP): A unified method for discovering RNA-interacting proteins, transcripts and genomic loci in situ.
Ashley F. Tsue, Evan E. Kania, Diana Q. Lei, Rose Fields, Christopher D. McGann, Elliot A. Hershberg, Xinxian Deng, Maryanne Kihiu, Shao‐En Ong, Christine M. Distèche, Sita Kugel, Brian J. Beliveau, Devin K. Schweppe, David M Shechner
The paper introduces O-MAP, a method for discovering RNA-interacting proteins, transcripts, and genomic loci in situ with high precision and without genetic manipulation.
bioRxiv · Jan 19, 2023 · PreprintMolecular Biology