Author

Muhammad Riaz Khan

Université de SherbrookeORCID 0000-0002-9786-8396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Jordan Filion· 1 shared Alexandre MaréchaliD· 1 shared Élie Méthot· 1 shared Erin Bonnell· 1 shared Gabriela Maia TeplitziD· 1 shared Isabelle Marois· 1 shared Jean-Christophe Dubois· 1 shared Julie FrioniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Jordan Filion

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1 paper

Recent·Most cited

The Single-Stranded DNA-Binding Factor SUB1/PC4 Alleviates Replication Stress at Telomeres and is a Vulnerability of ALT Cancer Cells

Jean-Christophe Dubois, Erin Bonnell, A. Jordan Filion, Julie Frion, Samuel Zimmer, Muhammad Riaz Khan, Gabriela Maia Teplitz, Lisa Casimir, Élie Méthot, Isabelle Marois, Mouhamed Idrissou, Pierre‐Étienne Jacques, Raymund J. Wellinger, Alexandre Maréchal

This paper identifies SUB1 as a vulnerability in ALT cancer cells by showing it mitigates telomeric replication stress and that its depletion synergizes with replication stress-inducing therapies.

Proceedings of the National Academy of Sciences · Jan 7, 2025Peer-reviewedCancer Biology