Peter G. Gillespie

The paper identifies a spontaneous mutation in the Ush1g gene in Neil1 knockout mice that causes an expanded phenotype including auditory and vestibular defects.

The paper uses cryo-tomography to model the actin core structure of mouse vestibular hair cell stereocilia lacking plastin 1, revealing structural features and gaps in actin filament organization.

This paper develops a method to rapidly freeze unfixed stereocilia for 3D imaging, revealing structural features of stereocilia in a near-native state.

This study identifies ELMOD1 as a GAP for ARF6 that stabilizes apical structures in vestibular hair cells by promoting ARF6-GTP hydrolysis.

This study investigates whether TRPV5, TRPV6, TRPM6, and TRPM7 contribute to hair-cell mechanotransduction and finds they are unlikely to be the pore-forming subunit of the transduction channel.