Manfred Auer

This study uses volume EM to reveal the three-dimensional structure of desmosomes in epithelial cells and identifies novel features like discontinuities in the outer dense plaque.

The paper uses cryo-tomography to model the actin core structure of mouse vestibular hair cell stereocilia lacking plastin 1, revealing structural features and gaps in actin filament organization.

This paper develops a method to rapidly freeze unfixed stereocilia for 3D imaging, revealing structural features of stereocilia in a near-native state.

Cryo-electron tomography and mechanical simulations revealed cell wall 3D architecture, optimized for flexibility/ductility.