Naoko Iida

Catalog of gut microbiota alterations associated with anticancer therapies across multiple cancer types

The paper analyzes gut microbiota changes across 264 cancer patients treated with 22 anticancer drugs, finding drug-specific and treatment-related microbiota alterations.

Systematically developing a registry of splice-site creating variants utilizing massive publicly available transcriptome sequence data

The paper develops a framework to identify splice-site creating variants (SSCVs) using transcriptome data, identifies 30,130 SSCVs, and demonstrates their therapeutic potential with ASOs.

A comprehensive workflow for target adaptive sampling long-read sequencing applied to hereditary cancer patient genomes

This study develops a computational workflow for target adaptive sampling long-read sequencing and applies it to hereditary cancer genomes to identify genetic variants and epigenetic changes.

Systematic identification of intron retention associated variants from massive publicly available transcriptome sequencing data

The paper identifies intron retention associated variants using transcriptome data alone, finding 27,937 variants and 3,077 putative disease-associated ones.