Author

Guido W Jenster

Erasmus MCORCID 0000-0002-8658-2552Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1

Frequent Co-Authors

Harmen J.G. van de WerkeniD· 3 shared Chris H. BangmaiD· 2 shared Youri HoogstrateiD· 2 shared Ágata Sofia Assunção CarreiraiD· 1 shared Alessandro QuattroneiD· 1 shared Andrew StubbsiD· 1 shared Anne S. Bolijn· 1 shared Anton M.F. KalsbeekiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBioinformatics

Harmen J.G. van de WerkenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell-Based Immunization Combined with Single-Round Cell Panning Enables Discovery of PSMA-Targeting Nanobodies from Phage Display Libraries

Tong Yang, Joke Veldhoven-Zweistra, Maarten Ligtenberg, Sigrun Erkens‐Schulze, Mirella S. Vredenbregt‐van den Berg, Rick Jansen, Patrick Chames, Eric M.J. Bindels, Khadijeh Ahmadi, Chris H. Bangma, Anton M.F. Kalsbeek, Janne Leivo, Nicolaas Lumen, Harmen J.G. van de Werken, Wytske M. van Weerden, , Guido W Jenster

This study demonstrates that non-targeted immunization and panning can isolate PSMA-targeting nanobodies from phage display libraries.

Biomolecules · Feb 14, 2026Peer-reviewedCancer Biology

CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells

Elena Gurrieri, Giulia Carradori, Michela Roccuzzo, Michael Pancher, Daniele Peroni, Romina Belli, Caterina Trevisan, Michela Notarangelo, Wenqiu Huang, Ágata Sofia Assunção Carreira, Alessandro Quattrone, Guido W Jenster, Timo L.M. ten Hagen, Vito D’Agostino

The paper investigates how CD81-guided extracellular vesicles interact with breast cancer cells and deliver cargo, showing HER2 receptor influence on tropism and drug efficacy.

Journal of Biomedical Science · Oct 14, 2024Peer-reviewedMolecular Biology

FASTAFS: file system virtualisation of random access compressed FASTA files

Youri Hoogstrate, Guido W Jenster, Harmen J.G. van de Werken

FASTAFS provides a filesystem virtualization solution for compressed FASTA files, enabling fast random access and metadata management.

BMC Bioinformatics · Nov 1, 2021Peer-reviewedBioinformatics

Detection of fusion transcripts and their genomic breakpoints from RNA sequencing data

Youri Hoogstrate, Malgorzata A. Komor, René Böttcher, Job van Riet, Harmen J.G. van de Werken, Stef van Lieshout, Ralf Hoffmann, Evert van den Broek, Anne S. Bolijn, Natasja F. J. Dits, Daoud Sie, David van der Meer, Floor Pepers, Chris H. Bangma, Geert J.L.H. van Leenders, , Guido W Jenster

Dr. Disco identifies fusion transcripts and genomic breakpoints using non poly(A)-enriched RNA-seq data, revealing transcribed rearrangements and their expression effects in cancer samples.

bioRxiv · May 17, 2021 · PreprintBioinformatics