Author

Zachary H. Walsh

Columbia University Irving Medical CenterORCID 0000-0002-9801-7892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alberto CicciaiD· 1 shared Benjamin IzariD· 1 shared D. Zack BrodtmaniD· 1 shared Gergő NikolényiiD· 1 shared Giuseppe LeuzziiD· 1 shared Johannes C. MelmsiD· 1 shared Joshua D. MilneriD· 1 shared Meri RogavaiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperImmunology

Alberto CicciaORCID

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1 paper

Recent·Most cited

ImmunologyNature BiotechnologyPeer-reviewedMay 23, 2024

Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells

Zachary H. Walsh, Parin Shah, Neeharika Kothapalli…·Benjamin Izar

This study uses base editing to screen for variants affecting T cell anti-tumor functions, identifying mutations that enhance tumor elimination with minimal off-target effects.

42 citationstop 2%

humanCRISPR screen

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