Meri Rogava

This study shows that a microbiome-dependent mechanism increases MHC-II expression in colon cancer cells, enhancing immunotherapy response and limiting metastasis.

This study uses base editing to screen for variants affecting T cell anti-tumor functions, identifying mutations that enhance tumor elimination with minimal off-target effects.

The paper uses Perturb-CITE-Seq to identify novel immune evasion mechanisms in cancer by analyzing multi-modal single-cell data from patient-derived models.