Author

Yi Wei Dong

Broad InstituteORCID 0000-0002-9802-4953Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Blake A. JohnsoniD· 2 shared Akshay NarkariD· 1 shared Albert Z. LiuiD· 1 shared Jasmin Coulombe‐HuntingtoniD· 1 shared Jin ZhuiD· 1 shared Keming LiiD· 1 shared Maged ZeineldiniD· 1 shared Mike TyersiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Blake A. JohnsonORCID

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2 papers

Recent·Most cited

Cell Ploidy Modulates Nucleolar Size via Dosage of Nucleolar Organizing Regions

Tianhao Bi, Varuni Rastogi, Maged Zeineldin, Blake A. Johnson, Yi Wei Dong, Mulin Li, Tatianna Larman

This study shows that aneuploidy alters nucleolar morphology by changing the number of nucleolar organizing regions (NORs), leading to enlarged nucleoli in cancer cells.

bioRxiv · Feb 16, 2026 · PreprintCancer Biology

The scaffold protein PRR14L links the PP2A-TACC3 axis to mitotic fidelity and sensitivity to MPS1 inhibition

Albert Z. Liu, Akshay Narkar, Keming Li, Thierry Bertomeu, Blake A. Johnson, Jasmin Coulombe‐Huntington, Yi Wei Dong, Jin Zhu, Mike Tyers, Rong Li

The paper identifies PRR14L as a gene affecting mitotic fidelity and sensitivity to MPS1 inhibition through a CRISPR/Cas9 screen and proximity labeling.

bioRxiv · Nov 4, 2025 · PreprintCell Biology