Author

Sara Borst

Children's Hospital of PhiladelphiaORCID 0000-0002-9829-1445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Brian EsteveziD· 1 shared Danuta Jadwiga Jarocha· 1 shared Deborah L. FrenchiD· 1 shared Hakon H. HakonarsoniD· 1 shared James P. GarifallouiD· 1 shared Kai TaniD· 1 shared Michael V. GonzaleziD· 1 shared Mortimer PoncziD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Brian EstevezORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintAug 23, 2020

RUNX1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells: Mechanistic studies and drug correction

Brian Estevez, Sara Borst, Danuta Jadwiga Jarocha…·Mortimer Poncz

This study shows that RUNX1 haploinsufficiency reduces megakaryocyte-biased hematopoietic progenitor cells and identifies drug targets to correct this defect.

1 citation

humanbulk RNA-seq

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