Author

Brian Estevez

Children's Hospital of PhiladelphiaORCID 0000-0002-1863-7224Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Danuta Jadwiga Jarocha· 1 shared Deborah L. FrenchiD· 1 shared Hakon H. HakonarsoniD· 1 shared James P. GarifallouiD· 1 shared Kai TaniD· 1 shared Michael V. GonzaleziD· 1 shared Mortimer PoncziD· 1 shared Nancy A. SpeckiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Danuta Jadwiga Jarocha

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1 paper

Recent·Most cited

RUNX1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells: Mechanistic studies and drug correction

Brian Estevez, Sara Borst, Danuta Jadwiga Jarocha, Varun S. Sudunagunta, Michael V. Gonzalez, James P. Garifallou, Hakon H. Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy A. Speck, Deborah L. French, , Mortimer Poncz

This study shows that RUNX1 haploinsufficiency reduces megakaryocyte-biased hematopoietic progenitor cells and identifies drug targets to correct this defect.

bioRxiv · Aug 23, 2020 · PreprintMolecular Biology