Author

Dave Smith

University of OxfordORCID 0000-0002-9845-5913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Frances M. PlattiD· 2 shared Alfonso Bueno‐OrovioiD· 1 shared Barry BolandiD· 1 shared C S SmithiD· 1 shared Charalampos SigalasiD· 1 shared Claire SmithiD· 1 shared David Priestman· 1 shared Duncan Burnaby SparrowiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

Frances M. PlattORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PhysiologybioRxivPreprintJul 9, 2026

Molecular and Structural Basis of Cardiac Remodelling in Niemann-Pick Type C

Qianqian Song, Ishika Prachee, Karolina M. Stępień…·Rebecca A.B. Burton

This study identifies cardiac involvement in Niemann-Pick type C through ECG abnormalities, fibrosis, and transcriptomic changes in patients and Npc1-/- mice.

DOI 10.64898/2026.07.05.736597

mousehuman

NeuroscienceBrain CommunicationsPeer-reviewedSep 15, 2020

Acetyl-Leucine slows disease progression in lysosomal storage disorders

Ecem Kaya, David Aitchison Smith, Claire Smith…·Frances M. Platt

This study shows that ADLL and its enantiomer ALL slow disease progression in lysosomal storage disorders through mechanisms involving glucose and antioxidant metabolism.

86 citationstop 3%

mousehuman