Author

Gabriel Birkuš

Czech Academy of Sciences, Institute of Organic Chemistry and BiochemistryORCID 0000-0002-9850-2150Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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Andrea EisenreichováiD· 1 shared Barbora NovotnáiD· 1 shared Dominika ChalupskáiD· 1 shared Evžen BouřaiD· 1 shared Karel ChalupskýiD· 1 shared Martin KlímaiD· 1 shared Michal ŠálaiD· 1 shared Milan DejmekiD· 1 shared

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1 shared paperMolecular Biology

Andrea EisenreichováORCID

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1 paper

Recent·Most cited

Molecular BiologyStructurePeer-reviewedFeb 6, 2024

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: structural basis of their function

Martin Klíma, Milan Dejmek, Vojtěch Duchoslav…·Evžen Bouřa

This study designs and synthesizes fluorinated cGAMP analogs that are stable against poxin cleavage and show high STING activation, with structural insights into their binding modes.

19 citations

experimental assay

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