Tao Wu

Expression spectrum of TE-derived transcripts in human adult tissues

The paper analyzes TE-derived transcripts in 17,329 human transcriptomes across 47 adult tissues, revealing their broad expression, sex-specific regulation, and contribution to protein diversity and metabolic functions.

MATES: A Deep Learning-Based Model for Locus-specific Quantification of Transposable Elements in Single Cell

MATES improves locus-specific transposable element quantification in single-cell data by accurately allocating multi-mapping reads using contextual alignment information.

Sparse CBX2 nucleates many Polycomb proteins to promote facultative heterochromatinization of Polycomb target genes

The paper shows sparse CBX2 nucleates Polycomb proteins to form condensates that regulate facultative heterochromatin and cellular differentiation in mESCs.