Abby Trouth

Rotational settings quantize nucleosome movement by chromatin regulators

The paper shows DNA sequence guides nucleosome rotation and positioning across species, with chromatin regulators navigating rather than overriding these settings.

Sparse CBX2 nucleates many Polycomb proteins to promote facultative heterochromatinization of Polycomb target genes

The paper shows sparse CBX2 nucleates Polycomb proteins to form condensates that regulate facultative heterochromatin and cellular differentiation in mESCs.

G1 length dictates H3K27me3 landscapes

The paper shows that G1 phase length regulates H3K27me3 levels in stem and tumor cells, with longer G1 increasing and shorter G1 decreasing H3K27me3.