Author

Tiara V. Hinton

Van Andel InstituteORCID 0000-0002-9868-3748Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexey G. Murzin· 1 shared Ayami OkuzumiiD· 1 shared Bernardino Francesco GhettiiD· 1 shared Catarina de Matos Ferraz FrancoiD· 1 shared Daisuke TaniguchiiD· 1 shared Daita KanedaiD· 1 shared Henry HouldeniD· 1 shared Hongwei ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Alexey G. Murzin

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1 paper

Recent·Most cited

Dimerisation and twist reversal of the Lewy fold in α-synuclein mutants with Parkinson's disease and dementia

Hongwei Zhang, Alexey G. Murzin, Jennifer A. Macdonald, Tiara V. Hinton, Sew‐Yeu Peak‐Chew, Catarina de Matos Ferraz Franco, Patrick W. Cullinane, Thomas T. Warner, Ayami Okuzumi, Raquel Real, Kenya Nishioka, Daisuke Taniguchi, Daita Kaneda, Huw R. Morris, Henry Houlden, , Michel Goedert

The paper reports the structures of α-synuclein filaments from individuals with Parkinson's disease and dementia, revealing differences in dimerisation and twist reversal between pathogenic and non-pathogenic variants.

bioRxiv · Apr 9, 2026 · PreprintBiophysics