Molecular BiologybioRxivPreprint
Computational docking reveals evolutionary conservation of a specific interaction between 15d-Prostaglandin-J2 and eIF4A.
So Jeong Yun, Hyunjoon Kim, Seung Gee Lee…·Woo Jae Kim
The paper uses computational docking to show that 15d-PGJ2 binds to eIF4A, blocking eIF4G interaction and forming stress granules, with conserved binding sites across species.
DOI 10.1101/237610