Cheol‐Hee Kim

Complementary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome

The paper develops murine and zebrafish Wac deletion models to study DeSanto-Shinawi Syndrome, finding craniofacial, behavioral, and neurodevelopmental phenotypes similar to the human condition.

Integrative Analysis of Proteomics and Metabolomics Reveals Impacts of Sam2 Knockout on Autism Spectrum Disorders

This study uses proteomics and metabolomics to identify molecular changes in Sam2 knockout mice, revealing altered pathways linked to autism spectrum disorder and anxiety.

Statistically unbiased prediction enables accurate denoising of voltage imaging data

SUPPORT is a self-supervised method that denoises voltage imaging data by leveraging spatiotemporal dependencies, preserving dynamics without requiring action potential information.

Computational docking reveals evolutionary conservation of a specific interaction between 15d-Prostaglandin-J2 and eIF4A.

The paper uses computational docking to show that 15d-PGJ2 binds to eIF4A, blocking eIF4G interaction and forming stress granules, with conserved binding sites across species.