Seung Gee Lee

Glia-specific expression of neuropeptide receptor Lgr4 regulates development and adult physiology in Drosophila

This study shows that glia-specific Lgr4 expression is essential for Drosophila development, adult behavior, and lifespan, with no effect when knocked down in neurons.

Multisensory inputs control the regulation of time investment for mating by sexual experience in male Drosophila melanogaster

Male Drosophila melanogaster adjust mating duration based on multisensory inputs from sexual experience to optimize reproductive investment.

Computational docking reveals evolutionary conservation of a specific interaction between 15d-Prostaglandin-J2 and eIF4A.

The paper uses computational docking to show that 15d-PGJ2 binds to eIF4A, blocking eIF4G interaction and forming stress granules, with conserved binding sites across species.

Sexually experienced male Drosophila melanogaster uses gustatory-to-neuropeptide integrative circuits to reduce time investment for mating

The paper identifies a behavioral plasticity in male fruit flies called Shorter-Mating-Duration (SMD) and shows it depends on specific neurons, brain regions, and neuropeptide signaling.