Activity-dependent structural plasticity of myelinated axons tunes their excitability
David J. Bennett, Vladimir Rančić, Temitayo O. Ayantayo, Zhenxiang Zhao, Mohammed Almokdad, Claire Francesca Meehan, Keith K. Fenrich, Ana M. Lucas‐Osma, Krishnapriya Hari
The paper shows that activity can rapidly thin myelinated axons, increasing their excitability, and that this change is reversible and clinically relevant.
bioRxiv · Oct 11, 2026 · PreprintNeuroscience