Turgay Akay

Posture and support geometry, rather than body size, dictate lateral dynamic stability in walking mammalian quadrupeds

The paper compares lateral dynamic stability in mice and cats, finding that smaller mammals are more stable due to crouched posture and wider steps, not body size.

Task-specificity of local load feedback depends on intersegmental information in an insect walking system

The study shows that load proprioceptive feedback in stick insects has direction-dependent effects on motor neuron activity during stepping, influenced by intersegmental signals.

Intrinsic spinal cord circuits compare sensory inputs and efference copies to correct for perturbations to ongoing movement

This study identifies dI3 neurons in the spinal cord that compare efference copies and sensory feedback to enable rapid movement corrections.

Widespread innervation of motoneurons by spinal V3 neurons globally amplifies locomotor output in mice.

The paper shows that V3 neurons in mice amplify locomotor output by increasing motoneuron excitability across all hindlimb muscles.

Distinct roles of spinal commissural interneurons in transmission of contralateral sensory information

The paper identifies the roles of V0 and V3 commissural interneurons in crossed reflexes in mice, showing V3 CINs are essential for both excitatory and inhibitory CRs, while V0 CINs modulate inhibitory CRs.

Orphan nuclear receptors Err2 and 3 promote a feature-specific terminal differentiationprogram underlying gamma motor neuron function and proprioceptive movement control

The paper identifies Err2 and Err3 as transcription factors promoting functional properties in gamma motor neurons essential for proprioceptive movement control.

The brain integrates proprioceptive information to ensure robust locomotion

This study shows that ascending proprioceptive information from the spinal cord to the brain is essential for responding to external perturbations during locomotion.

Multimodal sensory control of motor performance by glycinergic interneurons of the spinal cord deep dorsal horn.

This study identifies glycinergic inhibitory neurons in the spinal cord deep dorsal horn that integrate sensory inputs and modulate motor output during locomotion.

Freely behaving mice can brake and turn during optogenetic stimulation of the Mesencephalic Locomotor Region

This study shows that mice can brake and turn during optogenetic stimulation of the MLR, with speed and turn angle scaling to pre-turn speed.

Fractal analysis of muscle activity patterns during locomotion: pitfalls and how to avoid them

This paper investigates pitfalls in fractal analysis of EMG data during mouse locomotion and provides recommendations to avoid misinterpretation of Higuchis fractal dimension and Hurst exponent.

Modular organization of the murine locomotor pattern in presence and absence of sensory feedback from muscle spindles

The paper examines how muscle spindle feedback affects the modular organization of locomotion in mice, showing that proprioceptive input is crucial for maintaining motor function during walking and swimming.