Molecular BiologyCell Communication and SignalingPeer-reviewed
Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms
Antonio Rodríguez-Blázquez, Arturo Carabias, Alba Morán-Vaquero…·José M. de Pereda
This study identifies two distinct mechanisms by which Crk proteins activate C3G: adaptor-dependent interactions with specific motifs and phosphorylation-dependent priming.
14 citations