Author

Ross E. Granrath

University of Colorado AnschutzORCID 0000-0002-9899-831XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Angela L. RachubinskiiD· 2 shared Belinda A Enriquez Estrada· 2 shared Eleanor C. Britton· 2 shared Hannah R. LyfordiD· 2 shared Joaquin Maximiliano EspinosaiD· 2 shared Katherine A. WaughiD· 2 shared Keith P. SmithiD· 2 shared Kelly D. SullivaniD· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Angela L. RachubinskiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genetic & Genomic MedicineeLifePeer-reviewedDec 31, 2024

JAK inhibition decreases the autoimmune burden in Down syndrome

Angela L. Rachubinski, Elizabeth B. Wallace, Emily Gurnee…·Joaquin Maximiliano Espinosa

This study investigates immune dysregulation in Down syndrome and shows that JAK inhibition with tofacitinib reduces autoimmune symptoms and inflammatory markers without significant adverse effects.

9 citations

humanexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintFeb 3, 2022

Interferon receptor gene dosage determines multiple hallmarks of Down syndrome

Katherine A. Waugh, Ross Minter, Jessica A Baxter…·Joaquin Maximiliano Espinosa

The paper shows that correcting interferon receptor gene dosage in a mouse model of trisomy 21 rescues multiple key phenotypes associated with Down syndrome.

13 citations

mousebulk RNA-seq

𝕏 PostBluesky