Juan Carlos Leza

Disruption of Reelin signaling in a dual-hit mouse model of schizophrenia: impact of postnatal Δ9-tetrahydrocannabinol exposure in a maternal immune activation model

This paper develops a dual-hit mouse model of schizophrenia combining maternal immune activation and postnatal THC exposure, finding reduced Reelin levels and altered brain structure in treated mice.

Sex differences in the impact of nerve injury on Locus Coeruleus function and behaviour in mice

This study examines sex differences in LC function and behaviour following nerve injury in mice, finding distinct neurobiological and behavioural responses between males and females.

Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology.

This study examines kynurenine pathway (KP) alterations in post-mortem prefrontal cortex and cerebellum of schizophrenia patients, linking KP changes to monoamine metabolism and symptomatology.