Jone Razquin

This study develops a mouse model of locus coeruleus alpha-synuclein overexpression to investigate early Parkinson's disease features, finding functional and neurochemical disruptions without neuronal loss.

This study investigates how overexpression of the eIF4E gene in mice affects striatal long-term potentiation (LTP), finding increased LTP that is NMDA receptor-dependent but not blocked by D1/D2 receptor antagonists.

This study examines sex differences in LC function and behaviour following nerve injury in mice, finding distinct neurobiological and behavioural responses between males and females.

This study characterizes the lipidome of specific neuronal populations in mouse brain nuclei using imaging mass spectrometry, revealing sex-based differences in lipid profiles.

This study analyzes LC neuron firing patterns across species and biological factors, revealing diverse activity patterns and subregions enriched for specific factors and disease models.