Author

Hyehun Choi

Vanderbilt University Medical CenterORCID 0000-0002-9915-6632Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Fred S. LambiD· 2 shared Hong N. Nguyen· 2 shared Ryan J. StarkiD· 2 shared Sourav PanjaiD· 2 shared Julia K. RussolilloiD· 1 shared Sergey DikaloviD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersPhysiology

Fred S. LambORCID

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2 papers

Recent·Most cited

Smooth muscle LRRC8A knockout reduces superoxide influx, inflammation, senescence and atherosclerosis

Sourav Panja, Hyehun Choi, Hong N. Nguyen, Julia K. Russolillo, Sergey Dikalov, Ryan J. Stark, Fred S. Lamb

This study shows that knocking out LRRC8A in vascular smooth muscle cells reduces superoxide influx, inflammation, senescence, and atherosclerosis.

bioRxiv · Dec 29, 2025 · PreprintPhysiology

Smooth muscle LRRC8A knockout preserves vascular function in AngII hypertension

Hyehun Choi, Sourav Panja, Hong N. Nguyen, Ryan J. Stark, Fred S. Lamb

This study shows that LRRC8A knockout in vascular smooth muscle cells protects against AngII-induced vascular dysfunction and preserves BP dipping in hypertension.

Hypertension · Nov 4, 2025Peer-reviewedPhysiology