Author

Kevin J. Ranke

Central Michigan UniversityORCID 0000-0002-9916-1204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Amelia F. Alessi· 2 shared Benjamin S. OlsoniD· 2 shared Himani GalagaliiD· 2 shared Isaac T. SmithiD· 2 shared Kyal LalkiD· 2 shared Matthew J. WirickiD· 2 shared Mikayla N. Schmidt· 2 shared Xantha KarpiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Amelia F. Alessi

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintJun 18, 2025

daf-16/FOXO activity before dauer diapause anticipates dauer exit and post-dauer development via DAF-12/NHR

Matthew J. Wirick, Isaac T. Smith, Benjamin S. Olson…·Xantha Karp

This study shows that daf-16/FOXO activity before dauer diapause enables dauer exit and post-dauer development by promoting cholesterol retention and DAF-12 ligand synthesis.

DOI 10.1101/2025.06.18.660181

C. elegansexperimental assay

GeneticsPLoS GeneticsPeer-reviewedNov 15, 2021

daf-16/FOXO blocks adult cell fate in Caenorhabditis elegans dauer larvae via lin-41/TRIM71

Matthew J. Wirick, Allison R. Cale, Isaac T. Smith…·Xantha Karp

This study shows that daf-16/FOXO promotes multipotency in C. elegans dauer larvae by upregulating lin-41/TRIM71, which blocks premature adult cell fate markers.

12 citations

C. elegansstatistical model