Author
Johns Hopkins UniversityORCID 0000-0001-8983-6397Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Himani Galagali, Matthew J. Wirick, Amelia F. Alessi…·John K. Kim
This study identifies DAF-16/FOXO's role in repressing let-7 microRNA and NHR-23 to maintain multipotency during dauer in C. elegans.
Matthew J. Wirick, Isaac T. Smith, Benjamin S. Olson…·Xantha Karp
This study shows that daf-16/FOXO activity before dauer diapause enables dauer exit and post-dauer development by promoting cholesterol retention and DAF-12 ligand synthesis.
Ashwin Seetharaman, Himani Galagali, Elizabeth Linarte…·Gary Ruvkun
The paper shows that reduced synMuv B gene activity in C. elegans enhances RNA interference against viral infection.
Ruhi Patel, Himani Galagali, John K. Kim, Alison R. Frand
The paper identifies a feedback loop between NHR-23 and let-7 microRNAs that regulates molting cycles in C. elegans by controlling cycle frequency and number.
Matthew J. Wirick, Allison R. Cale, Isaac T. Smith…·Xantha Karp
This study shows that daf-16/FOXO promotes multipotency in C. elegans dauer larvae by upregulating lin-41/TRIM71, which blocks premature adult cell fate markers.