Author

Mikayla N. Schmidt

Central Michigan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Amelia F. Alessi· 2 shared Benjamin S. OlsoniD· 2 shared Himani GalagaliiD· 2 shared Isaac T. SmithiD· 2 shared Kevin J. RankeiD· 2 shared Kyal LalkiD· 2 shared Matthew J. WirickiD· 2 shared Xantha KarpiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Amelia F. Alessi

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2 papers

Recent·Most cited

daf-16/FOXO activity before dauer diapause anticipates dauer exit and post-dauer development via DAF-12/NHR

Matthew J. Wirick, Isaac T. Smith, Benjamin S. Olson, Amelia F. Alessi, Himani Galagali, Kyal Lalk, Mikayla N. Schmidt, Kevin J. Ranke, Lane S Rinkus, Xantha Karp

This study shows that daf-16/FOXO activity before dauer diapause enables dauer exit and post-dauer development by promoting cholesterol retention and DAF-12 ligand synthesis.

bioRxiv · Jun 18, 2025 · PreprintDevelopmental Biology

daf-16/FOXO blocks adult cell fate in Caenorhabditis elegans dauer larvae via lin-41/TRIM71

Matthew J. Wirick, Allison R. Cale, Isaac T. Smith, Amelia F. Alessi, Margaret R. Starostik, Liberta Cuko, Kyal Lalk, Mikayla N. Schmidt, Benjamin S. Olson, Payton M. Salomon, Alexis Santos, Axel D. Schmitter-Sánchez, Himani Galagali, Kevin J. Ranke, Payton Wolbert, , Xantha Karp

This study shows that daf-16/FOXO promotes multipotency in C. elegans dauer larvae by upregulating lin-41/TRIM71, which blocks premature adult cell fate markers.

PLoS Genetics · Nov 15, 2021Peer-reviewedGenetics