Author

Manuel A. Torres Acosta

Northwestern UniversityORCID 0000-0002-9939-7401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:DNA methylation· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anthony M. JoudiiD· 3 shared Benjamin David SingeriD· 3 shared Carla Patricia Reyes FloresiD· 3 shared Jonathan K. GurkaniD· 3 shared Kathryn A. HelminiD· 3 shared Luisa Morales‐NebredaiD· 3 shared Nurbek MambetsarieviD· 3 shared Qianli LiuiD· 3 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Anthony M. JoudiORCID

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3 papers

Recent·Most cited

Novel enzyme-based reduced representation method for DNA methylation profiling with low inputs

Qianli Liu, Kathryn A. Helmin, Zachary D. Dortzbach, Carla Patricia Reyes Flores, Manuel A. Torres Acosta, Jonathan K. Gurkan, Anthony M. Joudi, Nurbek Mambetsariev, Luisa Morales‐Nebreda, Mengjia Kang, Luke V. Rasmussen, Xóchitl G. Pérez-Leonor, Hiam Abdala‐Valencia, Benjamin David Singer

This paper introduces RREM-seq, an enzyme-based reduced representation DNA methylation sequencing method that enables high-resolution profiling of low-input samples, including clinical specimens.

Nucleic Acids Research · Jun 4, 2025Peer-reviewedGenomics

FOXP3+ Regulatory T Cells Require TBET to Regulate Activated CD8+ T Cells During Recovery from Influenza Infection

Nurbek Mambetsariev, Manuel A. Torres Acosta, Qianli Liu, Carla P. Reyes Flores, Anthony M. Joudi, Kathryn A. Helmin, Jonathan K. Gurkan, Elizabeth M. Steinert, Luisa Morales‐Nebreda, Benjamin David Singer

This study shows that FOXP3+ Treg cells use TBET to control activated CD8+ T cells during influenza recovery, but not Trm cell generation.

American Journal of Respiratory Cell and Molecular Biology · Apr 1, 2025Peer-reviewedImmunology

Maintenance DNA methylation is required for induced regulatory T cell reparative function following viral pneumonia

Anthony M. Joudi, Jonathan K. Gurkan, Qianli Liu, Manuel A. Torres Acosta, Kathryn A. Helmin, Luisa Morales‐Nebreda, Nurbek Mambetsariev, Carla Patricia Reyes Flores, Hiam Abdala‐Valencia, Elizabeth M. Steinert, Samuel Edward Weinberg, Benjamin David Singer

This study shows that DNA methylation via UHRF1 is essential for iTregs to promote lung recovery after viral pneumonia.

bioRxiv · Feb 25, 2025 · PreprintImmunology