Mengjia Kang

Novel enzyme-based reduced representation method for DNA methylation profiling with low inputs

This paper introduces RREM-seq, an enzyme-based reduced representation DNA methylation sequencing method that enables high-resolution profiling of low-input samples, including clinical specimens.

A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia

The paper examines alveolar T cell responses in SARS-CoV-2 pneumonia patients, finding that early interferon signaling and targeting of structural proteins correlate with better clinical outcomes.

Developing a standardized but extendable framework to increase the findability of infectious disease datasets

The paper develops a metadata schema based on Schema.org to improve the findability of infectious disease datasets and computational tools across repositories.