Author

William Robert Wilson

University of AucklandORCID 0000-0002-9939-8738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Cho Rong HongiD· 2 shared Michael P. HayiD· 2 shared Barbara A. LipertiD· 1 shared Benjamin D. DicksoniD· 1 shared David M. ShacklefordiD· 1 shared Gib BogleiD· 1 shared Jacqueline RossiD· 1 shared Jagdish Kumar JaiswaliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Cho Rong HongORCID

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2 papers

Recent·Most cited

RaDRI: A computational model for radiosensitisation by DNA double strand break repair inhibitors

Gib Bogle, Cho Rong Hong, Sophia F. O'Brien-Gortner, Barbara A. Lipert, Michael P. Hay, William Robert Wilson

RaDRI models radiosensitisation by DNA-PK inhibitors, showing that prolonged DNA-PK inhibition (~9 hours) achieves maximal radiosensitisation in DSB repair-proficient cells.

bioRxiv · Feb 21, 2026 · PreprintCancer Biology

Systemic CYP3A inhibition by ritonavir enables selective targeting of hypoxic tumour cells by prodrugs of DNA-PK inhibitors

Cho Rong Hong, Benjamin D. Dickson, Lydia P. Liew, Way Wua Wong, Jagdish Kumar Jaiswal, Stephen M. F. Jamieson, Jacqueline Ross, Longjin Zhong, David M. Shackleford, William Robert Wilson, Michael P. Hay

This paper shows that ritonavir enhances the hypoxia-targeted delivery of DNA-PK inhibitors, improving radiosensitization of tumors while sparing normal tissue.

bioRxiv · Feb 14, 2026 · PreprintPharmacology & Toxicology