Imogen L. Targett

Low-grade systemic inflammation stimulates microglial turnover and accelerates the onset of Alzheimer's-like pathology

This study shows that low-grade systemic inflammation accelerates Alzheimer's-like pathology by promoting microglial turnover and disease-associated microglia through the CSF1R pathway.

Traumatic stress history interacts with chronic peripheral inflammation to alter mitochondrial function of synaptosomes in a sex-specific manner

This study investigates how chronic stress and inflammation interact to affect mitochondrial function in synaptosomes, showing sex-specific differences in behavioral and metabolic outcomes.