Author

Adrián Olmos‐Alonso

Southampton General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Diego Gómez‐NicolaiD· 2 shared Monica Guerrero‐CarrascoiD· 2 shared Daniel Thomas· 1 shared David A. MenassaiD· 1 shared Gemma L. Fryatt· 1 shared Imogen L. TargettiD· 1 shared Juliane ObstiD· 1 shared María Martín‐EstebanéiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Diego Gómez‐NicolaORCID

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2 papers

Recent·Most cited

NeuroscienceGliaPeer-reviewedApr 10, 2024

Low-grade systemic inflammation stimulates microglial turnover and accelerates the onset of Alzheimer's-like pathology

Monica Guerrero‐Carrasco, Imogen L. Targett, Adrián Olmos‐Alonso…·Diego Gómez‐Nicola

This study shows that low-grade systemic inflammation accelerates Alzheimer's-like pathology by promoting microglial turnover and disease-associated microglia through the CSF1R pathway.

27 citationstop 5%

mouseexperimental assay

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NeuroscienceCell ReportsPeer-reviewedJun 1, 2021

Replicative senescence dictates the emergence of disease-associated microglia and contributes to Abeta pathology

Yanling Hu, Gemma L. Fryatt, Mohammadmersad Ghorbani…·Diego Gómez‐Nicola

This study shows that excessive microglial proliferation in Alzheimer's disease leads to replicative senescence and disease-associated microglia, contributing to Aβ pathology.

298 citationstop 1%

humanbulk RNA-seq

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