Monica Guerrero‐Carrasco

Low-grade systemic inflammation stimulates microglial turnover and accelerates the onset of Alzheimer's-like pathology

This study shows that low-grade systemic inflammation accelerates Alzheimer's-like pathology by promoting microglial turnover and disease-associated microglia through the CSF1R pathway.

Replicative senescence dictates the emergence of disease-associated microglia and contributes to Abeta pathology

This study shows that excessive microglial proliferation in Alzheimer's disease leads to replicative senescence and disease-associated microglia, contributing to Aβ pathology.