Gag proteins encoded by endogenous retroviruses are required for zebrafish development
Ni‐Chen Chang, Jonathan N. Wells, Andrew Y. Wang, Phillip Schofield, Yi-Chia Huang, Vinh H. Truong, Marcos Simões-Costa, Cédric Feschotte
This study shows that active endogenous retroviruses in zebrafish encode Gag proteins essential for embryonic development, with specific roles in mesoderm and neural crest formation.
Proceedings of the National Academy of Sciences · Apr 28, 2025Peer-reviewedDevelopmental Biology