Quirze Rovira

This study identifies MET signaling as a targetable vulnerability in rhabdoid tumors through integrated single-cell multi-omic and spatial transcriptomics analyses.

This study tracks T cell dynamics in a pediatric cancer patient post-ICI therapy to identify tumor-reactive TCRs for personalized TCR-T cell therapy.

The paper uses scRNA-seq to study NR2E3 mutations in mouse retinas, identifying hybrid photoreceptors and their role in disease.

This study characterizes zebrafish transposable elements (TEs) using bulk and single-cell RNA sequencing, revealing their dynamic genomic distribution and spatiotemporal expression patterns during embryogenesis.

The paper shows that during zygotic genome activation, embryos exhibit temporary splicing failures in DNA damage response genes, regulated by Snrpb and Snrpd2, which reduce DNA damage response.