Laquinimod treatment attenuates EAU by inhibiting both the inductive and effector phases in an APC-dependent manner
Biying Xu, Mary Joseph Mattapallil, Xiuzhi Jia, Jihong Tang, Reiko Horai, Rachel R Caspi, Igal Gery
This study shows Laquinimod reduces EAU by targeting AhR-expressing antigen-presenting cells, inhibiting T cell activation and promoting regulatory T cells.
bioRxiv · May 20, 2025 · PreprintImmunology