Biying Xu

Akkermansia expansion reduces short-chain fatty acid-producing Firmicutes in human-flora uveitis mice, raising Th1 responses and disease; a Verrucomicrobia/Firmicutes ratio is elevated in uveitis, MS and Crohn's patients.

This paper identifies trehalose monocorynomycolate (TMCM) from C. mast as a stimulator of IL-17-producing γδ T cells at the ocular surface, which protects against corneal infection.

This study shows Laquinimod reduces EAU by targeting AhR-expressing antigen-presenting cells, inhibiting T cell activation and promoting regulatory T cells.

This study demonstrates the successful integration and function of human iPSC-derived microglia in the mouse retina, mimicking endogenous microglial behavior and suggesting therapeutic potential for retinal diseases.