NeurosciencebioRxivPreprint
Degradation of amyloid beta species by multi-copper oxidases
Jing Yang, Kathleen Renee Ran, Wenzhe Ma…·Chongzhao Ran
This study identifies multi-copper oxidases (MCOs) as enzymes capable of degrading amyloid beta (Aβ) peptides, with ascorbate oxidase showing the strongest effect, and demonstrates their potential to mitigate Aβ-induced neuronal toxicity.
DOI 10.1101/2023.07.02.547398