Khondaker Miraz Rahman

This study reveals how AlbA, an antibiotic resistance regulator, differentially responds to albicidin and PBDs by structurally coupling ligand sensing to transcriptional activation.

The paper evaluates caged fluorescent probes for detecting beta-alanine aminopeptidase activity in bacterial species, showing selectivity for Pseudomonas aeruginosa, Burkholderia, and some Serratia strains, while being inactive in others.

This paper designs a pathway-selective P2Y1R inverse agonist that suppresses inflammation without affecting hemostasis, demonstrating its functional selectivity in vitro and in vivo.

This study shows Amphotericin B and Nystatin enhance SARS-CoV-2 replication in vitro by promoting viral entry, suggesting they should not be used in active COVID-19 cases.

This study identifies C7-substituted quinolines as potent inhibitors of AdeG efflux pumps in Acinetobacter baumannii, showing significant antibiotic potentiation and selectivity.

This paper constructs a drug hypersensitive Candida auris strain by deleting efflux pump genes, showing it is more effective for antifungal screening than wild-type strains.

This study investigates how amisulpride interacts with GLUT1 at the blood-brain barrier and how Alzheimer's disease affects this transport mechanism.

This study shows that changes in BBB transporters OCT1, PMAT, and MATE1 in Alzheimer’s disease increase sensitivity to amisulpride.