A genetic screen to uncover molecular mechanisms underlying lipid transfer protein function at membrane contact sites and neurodegeneration.
Shirish Mishra, Vaishnavi Manohar, Shabnam Chandel, Tejaswini Manoj, Subhodeep Bhattacharya, Nidhi Hegde, Vaisaly R Nath, Harini Krishnan, Corinne Wendling, Thomas Di Mattia, Arthur Martinet, Prasanth Chimata, Fabien Alpy, Padinjat Raghu
This study identifies suppressors of RDGB function in Drosophila and links them to novel lipids and ubiquitination processes in retinal degeneration and neurodevelopmental diseases.
bioRxiv · Jul 28, 2023 · PreprintNeuroscience