Selective MOSPD2-STARD3 interaction at ER contact sites governs late endosome/lysosome dynamics and cholesterol homeostasis
Céline Knorr, Mehdi Zouiouich, Julie Eichler, Maxime Boutry, Corinne Wendling, Sophie Huver, Arthur Martinet, Catherine Fromental-Ramain, Élodie Monsellier, Guillaume Drin, Catherine Tomasetto, Fabien Alpy
This study identifies MOSPD2-STARD3 as a functional unit regulating late endosome/lysosome dynamics and cholesterol homeostasis through selective interaction at ER contact sites.
bioRxiv · Mar 31, 2026 · PreprintCell Biology