Author

Harini Krishnan

National Centre for Biological SciencesORCID 0000-0002-7079-9909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Padinjat RaghuiD· 5 shared Shirish MishraiD· 2 shared Vaisaly R NathiD· 2 shared Aastha KumariiD· 1 shared Anil Vasudevan· 1 shared Arthur MartinetiD· 1 shared Avishek GhoshiD· 1 shared Corinne WendlingiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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5 shared papersNeuroscience

Padinjat RaghuORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The conserved biochemical activity and function of an early metazoan phosphatidylinositol 5 phosphate 4-kinase regulates growth and development.

Harini Krishnan, Suhail Muzaffar, Sanjeev Sharma, Ramya Visvanathan, Avishek Ghosh, Ramanathan Sowdhamini, Padinjat Raghu

This study identifies PIP4K as a conserved enzyme in early metazoans that regulates growth and development through insulin receptor signaling.

Journal of Cell Science · Jun 16, 2025Peer-reviewedBiochemistry

Ca2+ binding to Esyt is required to modulate membrane contact site density in Drosophila photoreceptors

Vaisaly R Nath, Harini Krishnan, Shirish Mishra, Padinjat Raghu

This study shows that Ca2+ binding to dEsyt modulates ER-PM MCS density in Drosophila photoreceptors, linking Ca2+ influx to signal transduction.

The Journal of Cell Biology · Jan 30, 2025Peer-reviewedCell Biology

A genetic screen to uncover molecular mechanisms underlying lipid transfer protein function at membrane contact sites and neurodegeneration.

Shirish Mishra, Vaishnavi Manohar, Shabnam Chandel, Tejaswini Manoj, Subhodeep Bhattacharya, Nidhi Hegde, Vaisaly R Nath, Harini Krishnan, Corinne Wendling, Thomas Di Mattia, Arthur Martinet, Prasanth Chimata, Fabien Alpy, Padinjat Raghu

This study identifies suppressors of RDGB function in Drosophila and links them to novel lipids and ubiquitination processes in retinal degeneration and neurodevelopmental diseases.

bioRxiv · Jul 28, 2023 · PreprintNeuroscience

IMPA1 dependent regulation of plasma membrane phosphatidylinositol 4,5-bisphosphate turnover and calcium signalling by lithium

Sankhanil Saha, Harini Krishnan, Padinjat Raghu

This study shows lithium inhibits IMPA1, reducing PIP2 resynthesis and calcium signaling in neural cells, leading to decreased neuronal excitability.

bioRxiv · Oct 14, 2022 · PreprintNeuroscience

Genomic sequencing of Lowe syndrome trios reveal a mechanism for the heterogeneity of neurodevelopmental phenotypes

Husayn Ahmed Pallikonda, Pramod Kumar Singh, Rajan S. Thakur, Aastha Kumari, Harini Krishnan, Ron George Philip, Anil Vasudevan, Padinjat Raghu

The paper identifies genetic variants contributing to clinical heterogeneity in Lowe syndrome by analyzing genomic data from affected family members.

bioRxiv · Jun 22, 2021 · PreprintGenomics