Author

Renuka Dahiya

University of SaskatchewanORCID 0000-0002-9976-5171Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alain Morejon Morales· 2 shared Anand KrishnaniD· 2 shared Andrew FreywaldiD· 2 shared Anjali SaxenaiD· 2 shared Ashtalakshmi Ganapathysamy· 2 shared Connor DenomyiD· 2 shared Érika Prando MunhoziD· 2 shared Frederick S. VizeacoumariD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alain Morejon Morales

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

Chelsea E. Cunningham, Frederick S. Vizeacoumar, Yue Zhang, Liliia Kyrylenko, Simon Both, Vincent Maranda, He Dong, Jared D. W. Price, Peng Gao, Konrad Wagner, Yingwen Wu, Mary Lazell-Wright, Ashtalakshmi Ganapathysamy, Rithik Hari, Kalpana Kalyanasundaram Bhanumathy, , Franco J. Vizeacoumar

The paper identifies synthetic dosage lethality targets for PLK1-overexpressing cancers using genome-wide screens and validates key hits to show their therapeutic potential.

Cell Genomics · May 9, 2025Peer-reviewedCancer Biology

Epigenetic Control of TERRA by FTSJ3 is Critical for Telomerase-Driven Cancers

Jared D. W. Price, Frederick S. Vizeacoumar, Omar Abuhussein, Vincent Maranda, Yue Zhang, Hironori Adachi, Liliia Kyrylenko, Aline Rangel Pozzo, He Dong, Li Hui Gong, Prachi Walke, Ashtalakshmi Ganapathysamy, Connor Denomy, Tanya Freywald, Renuka Dahiya, , Franco J. Vizeacoumar

The paper identifies FTSJ3 as a critical vulnerability in hTERT-overexpressing cancers by showing its role in TERRA methylation and telomeric heterochromatin stability.

bioRxiv · Jan 26, 2025 · PreprintCancer Biology