Anand Krishnan

This study shows that inhibiting MIF reduces mechanical hyperalgesia in CisIPN without affecting CP's anti-tumor effects.

This paper uses patient-derived pancreatic cancer organoids to identify drug sensitivities linked to tumor differentiation and pathway mutations, revealing new therapeutic targets in chemoresistant tumors.

This study establishes a DRG-nerve explant model for perineural invasion (PNI) and identifies molecular and cellular features of PNI in cancer cells.

This study shows that modifying Schwann cells to secrete MANF improves peripheral nerve regeneration in rats.

The paper identifies synthetic dosage lethality targets for PLK1-overexpressing cancers using genome-wide screens and validates key hits to show their therapeutic potential.

This study identifies Neurog2 as a potential therapeutic target for MYCN-driven neuroendocrine prostate cancer by showing its role in promoting tumor growth and NEPC development.

The paper identifies FTSJ3 as a critical vulnerability in hTERT-overexpressing cancers by showing its role in TERRA methylation and telomeric heterochromatin stability.