Sonia Taïb

This study identifies vascular dysfunction as a key contributor to oxaliplatin-induced peripheral neuropathy in mice by showing increased vasoconstriction and hypoxia, which can be mitigated by vasodilators.

The paper investigates the role of Netrin-1 and myelinating Schwann cells in regulating vascularization of the developing mouse sciatic nerve, showing Netrin-1 promotes vascular invasion during embryogenesis while Schwann cells reduce it postnatally.

This study shows that MLC1 is essential for postnatal development of the gliovascular unit, leading to vascular and fluid clearance defects in a mouse model of megalencephalic leukoencephalopathy.