Beatrice S. Melin

Genome-wide Polygenic Risk Scores Predict Risk of Glioma and Molecular Subtypes

This study develops a novel polygenic risk score (PRS-CS) for glioma that outperforms existing methods, improving risk prediction and subtype classification using genome-wide association study data.

A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences.

The paper reports a whole-genome sequenced control population from northern Sweden, revealing genetic substructure and improving variant imputation accuracy.

Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers

This study assesses polygenicity and risk prediction using common variants across 14 cancers, finding varying numbers of susceptibility variants and risk score effectiveness.