Melissa L. Bondy

This study analyzes a diverse glioma cohort to show ancestry influences on survival, somatic alterations, and mutational processes in diffuse gliomas.

This study develops a novel polygenic risk score (PRS-CS) for glioma that outperforms existing methods, improving risk prediction and subtype classification using genome-wide association study data.

This study uses Mendelian randomization and colocalization to identify 12 genes, three novel, associated with glioma risk across tissues and subtypes.

This study assesses polygenicity and risk prediction using common variants across 14 cancers, finding varying numbers of susceptibility variants and risk score effectiveness.