Author

Jaime E. Zlamal

Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0003-0029-024XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Andrei L. OstermaniD· 1 shared James E. KentiD· 1 shared Maarten VercruysseiD· 1 shared Marinela L. ElaneiD· 1 shared Semen A. LeyniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

Andrei L. OstermanORCID

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1 paper

Recent·Most cited

Microbiologynpj Antimicrobials and ResistancePeer-reviewedMar 2, 2024

Two Classes of DNA Gyrase Inhibitors Elicit Distinct Evolutionary Trajectories Toward Resistance in Gram-Negative Pathogens

Semen A. Leyn, James E. Kent, Jaime E. Zlamal…·Andrei L. Osterman

This study uses experimental evolution and whole genome sequencing to compare resistance mechanisms to GP6 and ciprofloxacin in E. coli and A. baumannii, finding distinct evolutionary trajectories dominated by efflux pump upregulation for GP6.

21 citations

E. coliArabidopsis

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